

A detailed description of the methods, background, and evidence summaries that support each of the recommendations can be found in the full text of the guidelines. The panel followed a process used in the development of other Infectious Diseases Society of America (IDSA) guidelines, which included a systematic weighting of the strength of recommendation and quality of evidence using the GRADE (Grading of Recommendations Assessment, Development, and Evaluation) system (Figure 1). In addition to diagnosis and management, recommended methods of infection control and environmental management of the pathogen are presented. difficile, or colonoscopic or histopathologic findings revealing pseudomembranous colitis. difficile toxins or detection of toxigenic C. CDI is defined by the presence of symptoms (usually diarrhea) and either a stool test positive for C. Summarized below are recommendations intended to improve the diagnosis and management of Clostridium difficile infection (CDI) in adults and children. Keywords: Clostridium difficile, Clostridioides difficile, Guidelines, CDI, CDAD, C.diff, C-diff Executive Summary This guideline updates recommendations regarding epidemiology, diagnosis, treatment, infection prevention, and environmental management. Although the prevalence of the epidemic and virulent ribotype 027 strain has declined markedly along with overall CDI rates in parts of Europe, it remains one of the most commonly identified strains in the United States where it causes a sizable minority of CDIs, especially healthcare-associated CDIs. difficile has established itself as an important community pathogen. Clostridium difficile remains the most important cause of healthcare-associated diarrhea and has become the most commonly identified cause of healthcare-associated infection in adults in the United States.

The update, which has incorporated recommendations for children (following the adult recommendations for epidemiology, diagnosis, and treatment), includes significant changes in the management of this infection and reflects the evolving controversy over best methods for diagnosis.

#California test 2017 practice update
